Hematopoietic Cellular Therapy and Transplant Program

Over the past two decades, Hematopoietic Cellular Therapy and Transplant (HCTT) has become an effective, life-saving procedure for a number of malignant and non-malignant diseases. For patients with hematologic malignancies and solid tumors, HCTT offers hope to many whose cancers are otherwise incurable.

Banner University Medical Center Tucson’s HCTT Program opened in 1988 and was the first of its kind in the Southwestern United States. The Program is affiliated with Banner University Medical Center, the University of Arizona College of Medicine and The University of Arizona Cancer Center. The full-service Adult and Pediatric combined program provides all types of transplant (allogeneic, autologous, and syngeneic) from related or unrelated donors for bone marrow, peripheral blood stem cell and cord blood.

Recently, the HCTT Program at Banner University Medical Center obtained approval as a CAR-T therapy provider through Kymriah (Novartis). This cutting edge therapy has the potential to cure otherwise dire forms of Leukemia by equipping the patient’s blood to ward off disease. BUMCT is the second provider in the state of Arizona to offer such therapy, and the only CAR-T provider in Southern Arizona.

Since July of 2000, The HCTT Program has been fully accredited by the Foundation for Accreditation of Cellular Therapy (FACT) for allogeneic and autologous bone marrow and peripheral blood progenitor cell transplantation, including cell collection and laboratory processing. In August, 1993, the program was fully accredited by the National Marrow Donor Program (NMDP) to perform matched unrelated allogeneic bone marrow transplants. BUMCT’s HCTT Program is now also a fully accredited marrow collection center for NMDP.

 

Team Approach: Optimal Care

Successful HCTT transplant requires concentrated effort from a team of experts. Banner University Medical Center’s HCTT Program coordinates the expertise of HCTT Providers, Nurse Coordinators, Unit Nurses, Nutritionists, Pharmacists, Quality and Social Workers to provide the highest levels of clinical care and family support for each patient. Multi-disciplinary rounds are conducted daily in both the Adult and Pediatric divisions. In addition, the HCTT Program meets weekly as a combined adult/pediatric multidisciplinary management team to discuss patients in the transplant evaluation phase, those currently undergoing transplant, and those in the post-transplant phase. The team reviews each step of the transplant journey to ensure all available resources and expertise are being invested in each HCTT patient.

 

Diseases for Which HCTT May be Indicated:  

Adult

Malignant Disease

  • Acute Lymphoblastic Leukemia
  • Acute Myeloid Leukemia
  • Chronic Myeloid Leukemia
  • Hodgkin’s Disease
  • Myelodysplastic Syndrome
  • Myeloproliferative Disorder
  • Myeloma
    • Amyloidosis
    • Plasma Cell Leukemia
    • POEMS Syndrome
    • Waldenstrom’s Disease
  • Non-Hodgkin’s Lymphoma
  • Other Acute Leukemias
    • Acute Biphenotypic Leukemia
    • Acute Promyelocytic Leukemia
    • Other Leukemias
    • Chronic Lymphocytic Leukemia
    • Prolymphocytic Leukemia
  • Solid Tumors
    • Central Nervous System Tumors
    • Ewing’s Sarcoma
    • Germ Cell
    • Histiocytic Sarcoma
    • Medulloblastoma
    • Testicular Tumors

Non-Malignant Disorders

  • Hemoglobinopathies
  • Aplastic Anemia
  • PHN

 

Pediatric

Malignant Disease

  • Acute Lymphoblastic Leukemia
  • Acute Myeloid Leukemia
  • Chronic Myeloid Leukemia
  • Hodgkin’s Disease
  • Myelodysplastic Syndrome
  • Solid Tumors
    • Atypical Teratoid Rhabdoid Tumor
    • Medulloblastoma
    • Central Nervous System Tumors
    • Ewings Sarcoma
    • Primitive Neuroectodermal Tumor
    • Germ Cell Tumor
    • Granulocytic Sarcoma
    • Hepatoblastoma
    • Neuroblastoma
    • Retinoblastoma
    • Wilms Tumor
    • Langerhans Cell Histiocytosis

Non-Malignant Disorders

  • Bone marrow failure/Hemoglobinopathy
    • Aplastic Anemia, Idiopathic
    • Fanconi’s Anemia
    • Congenital Dyserythropoietic Anemia
    • Kostmann Syndrome-Congenital Neutropenia
    • Severe Cyclic Neutropenia
    • Pure Red Cell Aplasia (Diamond-Blackfan anemia)
    • Congenital Amegakaryocytic Anemia
    • Sickle Cell Anemia
    • Thalassemia
  • Immune Deficiencies
    • Chediak-Higashi Syndrome
    • Chronic Granulomatous Disease
    • Lymphoproliferative Disorder
    • Hemophagocytic Lymphohistiocytosis
    • Severe Combined Immunodeficiencies
    • Wiskott Aldrich Syndrome
    • X-linked Lymphoproliferative Syndrome
    • Common Variable Immunodeficiency
    • Congenital Hair Hypoplasia
  • Metabolic disorders
    • Leukodystrophies
    • Mucopolysaccharidoses
    • I-cell disease

 

Types of Transplants Available at Banner University Medical Center

Donors

  • Autologous
  • Matched Related Allogeneic
  • Haploidentical Related Allogeneic
  • Mismatched Related Allogeneic
  • Matched Unrelated Allogeneic
  • Mismatched Unrelated Allogeneic

 

Sources

  • Bone Marrow
  • Peripheral Blood Stem Cell
  • Umbilical Cord Blood