Hanna (Johnny) Fares, PhD

Professor, Department of Molecular and Cellular Biology
Email Address: 
(520) 621-3709

Internal Contact Information

UACC Organizational Unit: 
Professional Bio: 

Dr. Fares joined the department of Molecular and Cellular Biology as an Assistant Professor in 2001.  He is currently professor and associate head of this department.  Dr. Fares studies basic mechanisms of lysosome formation and how defects in lysosome functions lead to various disorders.  Research is done on mammalian cell lines and in live Caenorhabditis elegans as a powerful genetic model

Research Information

Research Program: 
Cancer Biology
Member Status: 
Research Member
Year of Membership Acceptance: 
Summary of Research Activity: 

Lysosomal Storage Disorders

Selected Publications: 
  1. Miller, A., Schafer, J, Upchurch, C., Spooner, E., Huynh, J., Hernandez, S., McLaughlin, B., Oden, L., and Fares, H.  (2015). Mucolipidosis type IV protein TRPML1-dependent lysosome formation.  Traffic 16, 284-297.  PMID: 25491304
  2. Spooner, E., McLaughlin, B., Lepow, T., Durns, T. A., Randall, J., Upchurch, C., Miller, K., Campbell, E. M., and Fares, H.  (2013). Systematic Screens for Proteins that Interact with the Mucolipidosis type IV protein TRPML1.  PLOS ONE 8, e56780.  PMCID: PMC3572064
  3. Campbell, E. M. and Fares, H. (2010).  Roles of CUP-5, the Caenorhabditis elegans orthologue of human TRPML1, in lysosome and gut granule biogenesis.  BMC Cell Biology 11:40.  PMCID: PMC2891664
  4. Thompson, E. G., Schaheen, L., Dang, H., and Fares, H. (2007).  Lysosomal Trafficking Functions of mucolipin-1 in Murine Macrophages.  BMC Cell Biology 8:54. PMID: 18154673
  5. Schaheen, L., Patton, G., and Fares, H. (2006).  Suppression of the cup-5 Mucolipidosis Type IV-related lysosomal dysfunction by the inactivation of an ABC Transporter in C. elegans.  Development 133, 3939-3948. PMID: 16943270
  6. Schaheen, L., Dang, H., and Fares, H. (2006).  Basis of lethality in C. elegans lacking CUP-5, the Mucolipidosis Type IV orthologue. Developmental Biology 293, 382-391. PMID: 16530747
  7. Treusch, S., Knuth, S., Slaugenhaupt, S. A., Goldin, E., Grant, B. D., and Fares, H. (2004).  Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required  for lysosome biogenesis.  Proceedings of the National Academy of Science, USA 101,     4483-4488. PMID: 15070744

Professional Information

Professional Affiliations: 


2013-present  Professor, Department of Molecular & Cellular Biology
2012-present  Associate Chair, Department of Molecular & Cellular Biology
2010-2012      Interim Chair, Dept. of Molecular and Cellular Biology
2007-2013      Associate Professor, Dept. of Molecular and Cellular Biology
2003-present   Joint faculty, Department of Cell Biology and Anatomy, University of Arizona
2001-present   Member, Arizona Cancer Center
2001-2007      Assistant Professor, Dept. of Molecular and Cellular Biology

Academic Information

Post Doctoral: 
Columbia University, New York
University of North Carolina, Chapel Hill
Master's Degree: 
University of Michigan, Ann Arbor
Undergraduate School: 
American University of Beirut, Lebanon