Nafees Ahmad, PhD

Professor of Immunobiology
Director of Immunity and Infection
Email Address: 
Phone Number: 
(520) 626-7022
Professional Bio: 

The main focus of Dr. Nafees Ahmad’s laboratory is understanding the molecular mechanisms of human immunodeficiency virus type 1 (HIV-1) immunopathogenesis in aging and pediatric ptients. Areas of investigation include: immune aging factors associated with HIV disease in older infected patients, molecular and biological characterization of HIV-1 isolates; Genetic variability of HIV-1; Viral determinants, including viral heterogeneity, functional conservation/divergence of various HIV-1 genes, presence/absence of motifs in HIV-1 genes, replication efficiency, cell tropism, and cytopathic effects; Viral and host factors associated with HIV-1 evolution, replication, pathogenesis and disease progression in infected infants and children; Molecular mechanisms of HIV-1 infection in immature and mature mononuclear cells; Kinetics of HIV-1 replication in primary lymphocytes and monocytes/macrophages; Mechanisms of HIV-1 infection in immature and mature mononuclear cells, including entry and post-entry events, HIV-1 gene expression and T-cell development,  Biological activity of anti-HIV compounds in tissue culture system of T-cell lines, primary lymphocytes and monocytes/macrophages and receptor/coreceptor cell lines, Characterization of cellular factors in immature and mature mononuclear cells that may influence HIV replication differentially.

Research Information

Research Program: 
Non-programmatically Aligned
Member Status: 
Associate Research Member