Randy Burd, PhD

Asst Vice President for Program Innovation
Asst Director of Distance and Global Initiatives
Associate Professor, Bio5 Institute, Nutritional Sciences
Email Address: 
Phone Number: 
(520) 626-1863

UACC Information

UACC Organizational Unit: 
Professional Bio: 

Randy Burd, Ph.D. is the Assistant Vice President for Program Innovation in the Office of Global Initiatives.  He also serves as the Director of Distance and Global Initiatives in the College of Agriculture and Life Sciences, where he holds a faculty appointment as an Associate Professor of Nutritional Sciences. His role in these linked positions is to lead the expansion of new programs and initiatives to increase global presence.  He also has extensive expertise in technology and distance education and in developing international research and academic programs. 

Dr. Burd received his Ph.D. in Molecular and Cellular Biophysics in 1998 from the Roswell Park Cancer Institute in Buffalo, New York.  In 2002 he was appointed the director of Pre-Clinical Therapeutics at Thomas Jefferson University. In 2005 he was recruited to the University of Arizona to establish a Nutrigenomics program to identify new bioactive food compounds that could be developed into pharmaceuticals. In 2012 he assumed the role of Assistant Vice President for Program Innovation in Global Initiatives. His current research efforts focus on bioactive food compounds and he also publishes in the areas of technology and innovation.  He currently teaches a course in Nutrigenomics.  His research and education programs have been funded through various sources including international, federal, state, foundation and industrial sources.

Clinical Information

Disease or Clinical Specialty: 
Melanoma

Research Information

Research Program: 
Cancer Biology
Member Status: 
Research Member
Year of Membership Acceptance: 
2005
Summary of Research Activity: 

Current research interests in our laboratory focus on improving tumor radiation response through the use of biological response modifiers that alter tumor cell function, metabolism, cytokine stimulation and prostaglandin production, and affect aspects of tumor development, growth and treatment response. These include pharmaceutical drugs that are designed to specifically target tumors, bioactive nutritional components such as bioflavonoids, and compounds that regulate tumor glucose metabolism.

Selected Publications: 

Dr. Burd's NCBI bibliography

  1. Mars MM and Burd R. Impact over Profits: Toward a Social Entrepreneurship Model for University Technology Transfer. J Entrepreneurship & Organization Mgmt. 2013, In Press.
  2. The promise of digital (mobile) health in cancer prevention and treatment. Panayi ND, Mars MM, Burd R. Future Oncol 2013;9(5):613-7.
  3. Collection and visualization of dietary behavior and reasons for eating using twitter. Hingle M, Yoon D, Fowler J, Kobourov S, Schneider ML, Falk D, Burd R. J Med Internet Res 2013;24;15(6):e125.
  4. Mendoza EE, Pocceschi M, Kong X, Caro J, Limesand KH, Leeper DB, Burd R. Control of Glycolytic Flux by AMP-Activated Protein Kinase in Tumor Cells Adapted to Low pH, Translational Oncology, 2012;5(3):208-216.
  5. Martin KL, Hill GA, Klein RR, Arnett DG, Burd R, Limesand KH.  Prevention of radiation-induced salivary gland dysfunction utilizing a CDK inhibitor in a mouse model PLoS One 2012;7(12).
  6. Mendoza EE, Burd R. Quercetin as a systemic chemopreventative agent: structural and functional mechanisms. Mini Rev Med Chem. 2011 Dec 1;11(14):1216-21.
  7. Mitchell GC, Fillinger JL, Sittadjody S, Avila JL, Burd R, Limesand KH. IGF1 activates cell cycle arrest following irradiation by reducing binding of ΔNp63 to the p21 promoter. Cell Death Dis. 2010;1:e50.
  8. Vargas AJ, Sittadjody S, Thangasamy T, Mendoza EE, Limesand KH, Burd R. Exploiting tyrosinase expression and activity in melanocytic tumors: quercetin and the central role of p53. Integr Cancer Ther. 2011 Dec;10(4):328-40. Epub 2010 Dec 31.
  9. Victory K, Burd R, Fribley A, Sittadjody S, Arnett D, Klein RR, Limesand KH. Head and neck tumor cell radiation response occurs in the presence of IGF1. J Dent Res. 2011 Mar;90(3):347-52.
  10. Mitchell G, Fillinger J, Sittadjody S, Avila J, Burd R, Limesand K. IGF1 activates cell cycle arrest following irradiation by reducing binding of ΔNp63 to the p21 promoter. Cell Death Dis. 2010 Jun 10;2010(1):e50.
  11. Grundmann O, Fillinger JL, Victory KR, Burd R, Limesand KH. Restoration of radiation therapy-induced salivary gland dysfunction by post therapy IGF-1 administration. BMC Cancer. 2010 Aug 10;10:417.
  12. Vargas AJ, Burd R. Hormesis and synergy: pathways and mechanisms of quercetin  in cancer prevention and management. Nutr Rev. 2010 Jul;68(7):418-28.
  13. Thangasamy T, Sittadjody S, Mitchell GC, Mendoza EE, Radhakrishnan VM, Limesand KH, Burd R. Quercetin abrogates chemoresistance in melanoma cells by modulating deltaNp73. BMC Cancer. 2010 Jun 11;10:282. 
Collaborative Research: 
Ongoing:
2014-70003-22358                                  (Burd, PI)                                         10/01/14-09/31/17
USDA/CSREES  
Nanotechnology 2020.”
Proposal foci: to create a tri-university consortium designed to foster nanotechnology research and instructional activities specific to solving contemporary problems in agriculture and the health sciences. Health science students in cancer research will focus on magnetic nanoparticle therapies. The consortium will include nanotechnology centers and experts from the University of Arizona (UA), Northern Arizona University (NAU) and Johns Hopkins University (JHU). Specific consortium deliverables will include collaborative research and interdisciplinary courses that are highly adoptable by national and international nanotechnology programs. Targeted research projects will bring students from multiple universities together to solve common problems confronting society, furthering consortium value and preparing students for 2020 and beyond grand challenges in medicine.
Role: PI
 
5R01 DE023534-03                                   (Limesand/David, MPI)                    04/01/14-12/31/18                  
NIH/NIDCR
Functional Restoration through Salivary Progenitor Label Retaining Cells.
The long-term proposal goal is to evaluate whether novel therapies that promote apical-basal polarity within salivary stem/progenitor cells and their respective niches could improve clinical therapeutics for chronic salivary gland dysfunction and xerostomia following radiation therapy for head and neck cancer.
Role: Co-Investigator
 
2014-38420-21799                                  (Going/Burd, MPI)                           02/01/14-01/31/19                  
USDA/NIFA
National Needs Fellows Training Grant on Childhood Obesity
The goal of this grant is to train graduate students in nutrition and childhood obesity fields. Upon graduation, Fellows will have necessary skills to make significant contributions to research and programmatic initiatives aimed at childhood obesity prevention. Fellows will receive multidisciplinary training (coursework and experimental learning) contributing to core competencies, including team science, laboratory rotations, bench and clinical/translation, grant and publication writing, scientific presentations, dissertation research, online and formal teaching, and out-reach education projects. An in-country international research experience is also supported by the this program.
Role: Co-PI
 
4216990                                                    (Burd/Proctor, MPI)                         12/15/14-12/04/16              
INCA/SAGARPA (Mexico)
Binational Partnership in University Extension and Innovation.
This is a multinational and multi-university grant; initiative objective is to help engage Mexican universities to leverage health knowledge, information and technologies in order to provide a variety of improved health outcomes within rural communities.  The ultimate goal of this pilot project is to establish a network of institutions working together to implement university engagement in the development of rural and often poor Mexican communities. Technology transfer activities will be adapted to the needs and cultural conditions within Mexican rural communities.
Role: Co-PI
 
Completed:
5R01 DE018888-05                                   (Limesand, PI)                                 08/01/08-07/31/14       
NIH/NIDCR
Mechanisms of IGF1-mediated Rescue of Radiation-induced Salivary Gland Dysfunction
The general proposal goal was to identify mechanisms to preserve salivary gland function following exposure to radiation by evaluating cellular repair mechanisms and cell growth. The study results have the potential to prevent or restore salivary gland function to head and neck cancer patients.
Role: Co-Investigator
 
USDA-NIFA-CGP-0026                               (Burd, PI)                                        08/01/10-07/31/14      
USDA/NIFA
A Collaborative Mind-Mapping Solution to the Obesity Challenge
Project aims were to develop a new approach to obesity prevention research and education. We utilized technologies and developed a novel, web-based software platform to engage, support and train future and current interventionists in behavioral-based approaches to obesity prevention.
Role: PI
 
5R21 CA139183-02                                   (Burd, PI)                                        01/04/11-12/31/13      
NIH/NCI
Prevention of Melanoma by Targeting Tyrosinase with Dietary Quercetin
The proposed goals align with NIH Exploratory Cancer Prevention Studies Involving Molecular Targets for Bioactive Food Components program announcement. My project addressed the initiative to promote research focused on the identification and characterization of molecular targets for bioactive food components. Results provided a mechanistic basis and rationale for consumption of specific whole foods or supplementation to prevent cancer.
Role:PI

Professional Information

Positions and Honors: 
Positions:
2015-2016     Visiting Professor, Universidad de las Américas Puebla, Puebla, MX
2012-Present  Assistant Vice President for Program Innovation, Global Initiatives, UA
2012-Present  Assistant Director, Global Initiatives, UA College of Agriculture and Life Sciences
2011-Present  Associate Professor with Tenure, Department of Nutritional Sciences, UA
2005-2011     Assistant Professor, Department of Nutritional Sciences, The University of Arizona (UA)
2003-2005     Director, Pre-clinical Therapeutics, Department of Radiation Oncology, Thomas Jefferson U.
2002-2005     Assistant Professor, Department of Radiation Oncology, Thomas Jefferson University.
 
Adjunct Positions:
2005-2014     Adjunct Faculty, Department of Radiologic Sciences, Holy Family College
2004-Present  Adjunct Assistant Professor, Department of Radiation Oncology, Thomas Jefferson U.
2004-2012     Adjunct Faculty, Department of Radiological Sciences, Thomas Jefferson University
2001-2015     Associated Faculty, School of Radiation Therapy, Cooper Health System, NJ
 
Honors:
2014          International Faculty Lecturer, Universidad Estatal de Sonora, Hermosillo, MX
2012          Fellow, Bart Cardon Teaching Academy, The University of Arizona, Tucson, AZ
2012          Fellow, Academic Leadership Institute, The University of Arizona, Tucson, AZ
2011          Research Career Development Award, College of Agriculture & Life Sciences, University of Arizona, Tucson, AZ
2009          Bart Cardon Early Career Faculty Teaching Award, College of Agriculture & Life Sciences, University of Arizona, Tucson, AZ
2008          Lamda nu Lecturer, Radiation Biology Honor Society, Holy Family College, Philadelphia, PA
2004          Young Alumnus Achievement Award, University College at Buffalo, Buffalo, NY
2004          David Vernon Bullough Award for Academic Excellence in Biology, University College at Buffalo, Buffalo, NY
1994          Cum Laude, University College at Buffalo, Buffalo, NY
 
Journal:
2014-Present  Nutrition and Cancer, Editorial Board
2012-Present  Journal of Food and Nutritional Disorders, Founding Editorial Board
2010-2014     Nutrition and Cancer, Associate Editor
 
Grant review:
2014          Partners of the Americas 100K Strong Round Five
2012          Defense Threat Reduction Agency, Production of Reactive Oxygen Species in Cancer Stem Cells Subsequent to Acute Radiation Exposure, Scientific Reviewer
2011          USDA Higher Education Challenge Review Panel, Scientific Reviewer
2010          Department of Defense, BCRP Clinical & Experimental Therapeutics #1, Scientist Reviewer
2009          Department of Defense, BCRP Concept-Cell Biology #2, Online Reviewer
2008          Department of Defense, Breast Cancer Research Program (BCRP) Clinical & Experimental Therapeutics #1, Scientist Reviewer
Other Experience and Professional Memberships/Affiliations: 
American Association for Cancer Research
North American Hyperthermia Society
Radiation Research Society

Academic Information

Post Doctoral: 
Thomas Jefferson University, 2002
Doctorate: 
PhD, University at Buffalo, Roswell Park Cancer Inst., 1998
Undergraduate School: 
BA, Biological Sciences, University College at Buffalo, 1994