Dr. Campos earned his PhD from Rice University in 2005, studying the biology of adenoviral gene therapy vectors and vector targeting in the laboratory of Michael Barry now at Mayo Clinic in Rochester, MN. He then trained as a postdoc from 2005-2008 with Michelle Ozbun at the University of New Mexico, focusing on human papillomavirus (HPV) infection. He came to The University of Arizona in 2008 as an assistant research professor in the BIO5 Institute and joined the Department of Immunobiology as an assistant professor in 2011.
The high risk human papillomaviruses (HPVs) are the most prevalent sexually transmitted infections and are responsible for 5% of cancers worldwide. These oncogenic viruses establish persistent infections in the mucosal epithelium. Dr. Campos' broad interests are towards HPV-cell interactions and the biology of capsid structure, viral entry, trafficking, uncoating, membrane penetration, and the innate cellular responses to viral infection. Ultimately his work will not only identify potential target molecules and processes for development of prophylactic antiviral drugs and compounds, but it will broaden our fundamental understanding of HPV biology and viral mechanisms of immune evasion and persistence.
- Christakos, K. J., J. A. Chapman, B. A. Fane, and S. K. Campos, "PhiXing-it, displaying foreign peptides on bacteriophage ΦX174.", Virology, vol. 488, pp. 242-8, 2016 Jan 15. PMID: 26655242
- Bronnimann, M. P., C. M. Calton, S. F. Chiquette, S. Li, M. Lu, J. A. Chapman, K. N. Bratton, A. M. Schlegel, and S. K. Campos, "Furin Cleavage of L2 During Papillomavirus Infection: Minimal Dependence on Cyclophilins.", J Virol, 2016 Apr 27. PMID: 27122588
- Campos, S. K., "New structural model of adenoviral cement proteins is not yet concrete.", Proc Natl Acad Sci U S A, vol. 111, issue 43, pp. E4542-3, 2014 Oct 28. PMCID: PMC4217438 PMID: 25304640
- Bronnimann, M. P., J. A. Chapman, C. K. Park, and S. K. Campos, "A transmembrane domain and GxxxG motifs within L2 are essential for papillomavirus infection.", J Virol, vol. 87, issue 1, pp. 464-73, 2013 Jan. PMCID: PMC3536380 PMID: 23097431
- Calton, C. M., A. M. Schlegel, J. A. Chapman, and S. K. Campos, "Human papillomavirus type 16 does not require cathepsin L or B for infection.", J Gen Virol, vol. 94, issue Pt 8, pp. 1865-9, 2013 Aug. PMID: 23677785
- Campos, S. K., J. A. Chapman, M. J. Deymier, M. P. Bronnimann, and M. A. Ozbun, "Opposing effects of bacitracin on human papillomavirus type 16 infection: enhancement of binding and entry and inhibition of endosomal penetration.", J Virol, vol. 86, issue 8, pp. 4169-81, 2012 Apr. PMCID: PMC3318660 PMID: 22345461
- Marušič, M. Bergant, M. A. Ozbun, S. K. Campos, M. P. Myers, and L. Banks, "Human papillomavirus L2 facilitates viral escape from late endosomes via sorting nexin 17.", Traffic, vol. 13, issue 3, pp. 455-67, 2012 Mar. PMCID: PMC3276720 PMID: 22151726
- Campos, S. K., and M. A. Ozbun, "Two highly conserved cysteine residues in HPV16 L2 form an intramolecular disulfide bond and are critical for infectivity in human keratinocytes.", PLoS One, vol. 4, issue 2, pp. e4463, 2009. PMCID: PMC2636891 PMID: 19214230