Yira Bermudez, PhD, MBA, RAC

Regulatory Affairs Officer/Assistant Professor of Medicine

Phone Number: 
(520) 626-7254

Clinical Information

Disease or Clinical Specialty: 
Actinic Keratosis
Basal Cell Cancer
Cancer Prevention
Nonmelanoma Skin Cancer
Skin Cancer
Squamous Cell Carcinoma

Research Information

Research Program: 
Cancer Prevention and Control
Member Status: 
Affiliate Member
Year of Membership Acceptance: 
Selected Publications: 

a.     Journal Articles

1.     Bermudez Y, Stratton SP, Curiel-Lewandrowski C, Warneke JA, Hu C, Bowden GT, Dickinson SE, Dong Z, Bode AM, Saboda K, Brooks C, Petricoin E 3rd, Hurst C, Alberts DS, Einspahr JG. Activation of the PI3K/Akt/mTOR and MAP kinase Signaling Pathways in Response to Acute Solar Simulated Light Exposure of Human Skin. Cancer Prev Res (Phila). 2015 Jun 11. PMID:26031292

2.     Curiel-Lewandrowski C, Tang JY, Einspahr JG, Bermudez Y, Hsu CH, Rezaee M, Lee AH, Tangrea J, Parnes HL, Alberts DS, Chow HH. Pilot Study on the Bioactivity of Vitamin D in the Skin after Oral Supplementation. Cancer Prev Res (Phila). 2015 Apr 2. PMID:25835512

3.     Bermudez Y. Ultraviolet Involvement in Melanocyte Transformation to Melanoma. Br J Dermatol. 2014 Dec;171(6):1289. PMID:25523253

4.     Williams JD, Bermudez Y, Stratton SP, Wondrak GT. Protein-epitopes formed in Sun Damaged Human Skin from Lipid Peroxidation are Mediators of Cutaneous Photo-oxidative Stress. J Photochem Photobiol B. 2014 Mar 5;132:56-65. PMID:24584085

5.     Einspahr JG, Calvert V, Alberts DS, Curiel-Lewandrowski C, Warneke J, Krouse R, Liotta L, Longo C, Pellicani G, Prasad A, Sagerman P, Bermudez Y, Deng J, Bowden GT, and Petricoin EF III. Functional Protein Pathway Activation Mapping of the Progression of Normal Skin to Squamous Cell Carcinoma. Cancer Prev Res (Phila) 2012 Mar;5(3):403-413. PMID:22389437

6.     Bermudez Y, Benavente CA, Meyer RG, Coyle WR, Jacobson MK, Jacobson EL.  Nicotinic Acid Receptor Abnormalities in Human Skin Cancer: Implications for a Role in Epidermal Differentiation. PLoS ONE. 2011;6(5):e20487. PMID:21655214

7.     Anderson NS, Bermudez Y, Badgwell D, Chen R, Nicosia SV, Bast RC, Kruk PA. Urinary Levels of Bcl-2 are Elevated in Ovarian Cancer Patients. Gynecol Oncol 2009 Jan;112(1) 60-67. PMID:19007973

8.     Bermudez Y, Yang H, Cheng JQ, Kruk PA. Pyk2/ERK 1/2 Mediate Sp1- and c-Myc-Dependent Induction of Telomerase Activity by Epidermal Growth Factor. Growth Factors 2008 Feb;26(1):1-11. PMID:18365874

9.     Bermudez Y, Yang H, Saunders BO, Cheng JQ, Nicosia SV, Kruk PA. VEGF and LPA Induce Telomerase in OvarianCancer. Gynecol Oncol 2007 Sep;106(3):526-537. PMID:17559911

10.  Bermudez Y, Ahmadi S, Lowell NE, Kruk PA. Vitamin E Suppresses Telomerase Activity in Ovarian Cancer Cells. Cancer Detect Prev. 2007;31(2):119-128. PMID:17335992

11.  Bermudez Y, Erasso D, Johnson NC, Alfonso-De Matte MY, Lowell NE, Kruk PA. Telomerase Confers Resistance to Caspase-Mediated Apoptosis. Clin Interv Aging. 2006;1(2) 155-167. PMID: 18044112

b.     Book Chapter

Bermudez Y, Cordova K, Williams JD. Folate Nutrition in Skin Health and Skin Cancer Prevention. Bioactive Dietary Factors and Plant Extracts in Dermatology. 2012: Part V Chapter 22 Page 229-256

Professional Information

  • UA College of Medicine AAMC 2014 Minority Faculty Career Development, September 2014
  • The University of Arizona Skin Cancer Institute, Pilot Project Grant Recipient, December 2013
  • The University of Arizona Skin Cancer Institute, Pilot Project Grant Recipient, September 2011
  • AACR Translational Cancer Research for Basic Scientists Workshop, October 2010
  • National Institute of Health (NIH) Loan Repayment Program Award, August 2008
  • ASPO New Investigators Workshop Participant Award, March 2008

Academic Information

Undergraduate School: 
University of Tampa